Defective Genes & Disease

Take Control of your DNA

Defective Genes "Cause" Less Than 1% Of All Disease

by Sayer Ji

In the mainstream media (and the popular consciousness programmed to consume it) defective genes are spoken about as if they were "disease time bombs," fatalistically programmed to go off inside of us, thanks to flawed genetic contributions of our ancestors. And yet, despite common misconceptions, monogenic diseases, or diseases that result from errors in the nucleotide sequence of a single gene are exceedingly rare.  In fact, less than 1% of all diseases fall within this category...

Following the completion of the Human Genome Project (HGP) in 2003 it is no longer accurate to say that our genes “cause” disease, any more than it is accurate to say that DNA is sufficient to account for all the proteins in our body. Despite initial expectations, the HGP revealed that there are only 20,000-25,000 genes in human DNA (genome), rather than the 100,000 + believed necessary to encode the 100,000 + proteins found in the human body (proteome). Did you follow that?  

There are not even enough genes in the human body to account for the existence of the basic protein building blocks that make it possible, much less explain the behavior of these proteins in health and disease states! 

The “blueprint” model of genetics: one gene → one protein → one cellular behavior, which was once the holy grail of biology, has now been supplanted by a model of the cell where epigenetic factors (literally: “beyond the control of the gene”) are primary in determining how DNA will be interpreted, translated and expressed. A single gene can be used by the cell to express a multitude of proteins and it is not the DNA itself that determines how or what genes will be expressed. Rather, we must look to the epigenetic factors to understand what makes a liver cell different from a skin cell or brain cell. All of these cells share the exact same 3 billion base pairs that make up our genetic code, but it is the epigenetic factors, e.g. regulatory proteins and post-translational modifications, that make the determination as to which genes to turn on and which to silence, resulting in each cell’s unique phenotype.

Moreover, epigenetic factors are directly and indirectly influenced by the presence or absence of key nutrients in the diet, as well as exposures to chemicals, pathogens and other environmental influences. Thoughts and emotions also play a role in how these epigenetic factors are articulated, indicating that the flow of genetic information, once thought to be strictly vertical (passage of genetic information from one cell or individual organism to its progeny by conventional heredity mechanisms), also flows horizontally and bi-directionally, opening the door back up for the human soul to return to biological science, having been reduced to a mere "ghost in the machine," since René Descartes (1596-1650), the French philosopher and mathematician, split body and soul asunder, almost five centuries ago.

In a nutshell, what we eat and what we are exposed to in our environment directly affects our DNA and its expression.

Within the scope of this new perspective even classical monogenic diseases like Cystic Fibrosis (CF) can be viewed in a new, more promising light. In CF many of the adverse changes that result from the defective expression of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene may be preventable or reversible, owing to the fact that the misfolding of the CFTR gene product has been shown to undergo partial or full correction (in the rodent model) when exposed to phytochemicals found in turmeric, cayenne, and soybean Moreover, nutritional deficiencies of seleniun, zinc, riboflavin, vitamin e, etc. in the womb or early in life, may “trigger” the faulty expression or folding patterns of the CFTR gene in Cystic Fibrosis which might otherwise have avoided epigenetic activation. This would explain why it is possible to live into one’s late seventies with this condition, as was the case for Katherine Shores (1925-2004). The implications of these findings are rather extraordinary: epigenetic and not genetic factors are primary in determining disease outcome. Even if we exclude the possibility of reversing certain monogenic diseases, the basic lesson from the post-Genomic era is that we can’t blame our DNA for causing disease. Rather, it may have more to do with what we choose to expose our DNA to, and even more surprisingly: how we choose to think and feel about our embodiment.

Neotame

Neotame the next aspartame? FDA doesn't require labeling of latest chemical sweetener from Monsanto  

It could be lurking in the foods you eat every single day, including U.S. Department of Agriculture (USDA) certified organic foods, and you would never even know it. The U.S. Food and Drug Administration (FDA) has declared that one of Monsanto's latest creations, a synthetic sweetener chemical known as neotame, does not have to be labeled in food products, including even in organic food products.  

A modified version of aspartame with even more added toxicity, neotame received quiet and unassuming FDA approval back in 2002, even though no safety studies have ever been conducted on the chemical (http://www.neotame.com/pdf/neotame_fda_US.pdf). In fact, an investigation conducted by Feingold.org found only four studies relating to neotame in the MEDLINE database.  

Two of these "studies" were not studies at all, and the other two were actually one duplicate study conducted by NutraSweet, the company that produces and sells neotame.  

So just like with aspartame, the FDA has once again approved for use a dangerous sweetener chemical that metabolizes into formaldehyde when consumed. Except this time, the chemical contains added 3-dimethylbutyl, which the U.S. Environmental Protection Agency (EPA) has listed as one of the most hazardous known chemicals, and it does not have to be labeled on any of the products to which it is added.  

"Neotame has similar structure to aspartame -- except that, from it's structure, appears to be even more toxic than aspartame," writes HolisticMed.com on its page about neotame. "Like aspartame, some of the concerns include gradual neurotoxic and immunotoxic damage from the combination of the formaldehyde metabolite (which is toxic at extremely low doses) and the excitotoxic amino acid" (http://www.holisticmed.com/neotame/toxin.html).

The FDA, the European Food Safety Agency (EFSA), and the World Health Organization (WHO) all consider neotame to be safe for use, despite the fact that WHO actually published a paper seeking to establish acceptable daily intake levels for neotame. If neotame is so safe that it does not even have to be labeled, according to the FDA, then why do acceptable daily intake levels have to be established? And what is the point of establishing them in the first place?  

This dog and pony show of special interest regulatory corruption is a travesty that will have global negative health consequences. Like most other toxins added to foods, neotame will most likely cause chronic damage over a long period of time, which means mainstream health authorities will get away with never having to admit that neotame is a dangerous toxin. 

That's all we need...another chemical sweetener!  The best thing you can do for your health is to try eat as pure and unprocessed as possible.  Know what you put in your body as best as you can. 

What Monsanto Doesn't Want You To Know

What Monsanto Doesn't Want You To Know...The Genetic Conspiracy

The last couple blog posts I have focused on GMO foods.  Please educate yourself about what you eat to make healthier choices for your health and well being.  

 

How GMO foods alter organ function and pose a very real health threat to humans

2/2/2012 - So disturbing- Click here to watch video

 

You are what you eat- no longer just a phrase!

1/24/2012 - So disturbing- Click here to watch video 

 

What is GMO?

Agricultural Crops That Have a Risk of Being GMO

For consumers, it can be difficult to stay up-to-date on food ingredients that are at-risk of being genetically modified, as the list of at-risk agricultural ingredients is frequently changing. As part of the Non-GMO Project’s commitment to informed consumer choice, we work diligently to maintain an accurate list of risk ingredients. 

Agricultural products are segmented into two groups: 

(1) those that are high-risk of being GMO because they are currently in commercial production, and (2) those that have a monitored risk because suspected or known incidents of contamination have occurred and/or the crops have genetically modified relatives in commercial production with which cross-pollination (and consequently contamination) is possible. For more information on the Non-GMO Project’s testing and verification of risk ingredients and processed foods, please see the Non-GMO Project Standard.

High-Risk Crops (in commercial production; ingredients derived from these must be tested every time prior to use in Non-GMO Project Verified products (as of December 2011):

• Alfalfa (first planting 2011)
• Canola (approx. 90% of U.S. crop)
• Corn (approx. 88% of U.S. crop in 2011)
• Cotton (approx. 90% of U.S. crop in 2011)
• Papaya (most of Hawaiian crop; approximately 988 acres)
• Soy (approx. 94% of U.S. crop in 2011)
• Sugar Beets (approx. 95% of U.S. crop in 2010)
• Zucchini and Yellow Summer Squash (approx. 25,000 acres)

ALSO high-risk: animal products (milk, meat, eggs, honey, etc.) because of contamination in feed.

Monitored Crops (those for which suspected or known incidents of contamination have occurred, and those crops which have genetically modified relatives in commercial production with which cross-pollination is possible; we test regularly to assess risk, and move to “High-Risk” category for ongoing testing if we see contamination):

• Beta vulgaris (e.g., chard, table beets)
• Brassica napa (e.g., rutabaga, Siberian kale)
• Brassica rapa (e.g., bok choy, mizuna, Chinese cabbage, turnip, rapini, tatsoi)
• Curcubita (acorn squash, delicata squash, patty pan)
• Flax
• Rice

Common Ingredients Derived from GMO Risk Crops
Amino Acids, Aspartame, Ascorbic Acid, Sodium Ascorbate, Vitamin C, Citric Acid, Sodium Citrate, Ethanol, Flavorings (“natural” and “artificial”), High-Fructose Corn Syrup, Hydrolyzed Vegetable Protein, Lactic Acid, Maltodextrins, Molasses, Monosodium Glutamate, Sucrose, Textured Vegetable Protein (TVP), Xanthan Gum, Vitamins, Yeast Products.

You may also be wondering about…

• Tomatoes: In 1994, genetically modified Flavr Savr tomatoes became the first commercially produced GMOs. They were brought out of production just a few years later, in 1997, due to problems with flavor and ability to hold up in shipping. There are no genetically engineered tomatoes in commercial production, and tomatoes are considered “low-risk” by the Non-GMO Project Standard.
• Potatoes: Genetically modified NewLeaf potatoes were introduced by Monsanto in 1996. Due to consumer rejection  several fast-food chains and chip makers, the product was never successful and was discontinued in the spring of 2001. There are no genetically engineered potatoes in commercial production, and potatoes are considered “low-risk” by the Non-GMO Project Standard.
• Wheat: There is not currently, nor has there ever been, any genetically engineered wheat on the market. Of all “low-risk” crops, this is the one most commonly (and incorrectly) assumed to be GMO. It is a key commodity crop, and the biotech industry is pushing hard to bring GMO varieties to market. The Non-GMO Project closely watches all development on this front.
• Salmon: A company called AquaBounty is currently petitioning the FDA to approve its genetically engineered variety of salmon, which has met with fierce consumer resistance. Find out more here.
  
• Pigs: A genetically engineered variety of pig, called Enviropig has been developed by scientists at the University of Guelph. A February 2010 statement issued by the University of Guelph contained the following information: ”Applications to other federal agencies to assess the safety of Enviropigs for human food and animal feed were currently under review both in the U.S. and Canada and there is no set date when or if these reviews will conclude.”

GMO Facts

What are GMOs?
GMOs, or “genetically modified organisms,” are plants or animals created through the gene splicing techniques of biotechnology (also called genetic engineering, or GE). This experimental technology merges DNA from different species, creating unstable combinations of plant, animal, bacterial and viral genes that cannot occur in nature or in traditional crossbreeding.

Virtually all commercial GMOs are engineered to withstand direct application of herbicide and/or to produce an insecticide. Despite biotech industry promises, none of the GMO traits currently on the market offer increased yield, drought tolerance, enhanced nutrition, or any other consumer benefit.

Meanwhile, a growing body of evidence connects GMOs with health problems, environmental damage and violation of farmers’ and consumers’ rights.

Are GMOs safe?
Most developed nations do not consider GMOs to be safe. In nearly 50 countries around the world, including Australia, Japan, and all of the countries in the European Union, there are significant restrictions or outright bans on the production and sale of GMOs. In the U.S., the government has approved GMOs based on studies conducted by the same corporations that created them and profit from their sale. Increasingly, Americans are taking matters into their own hands and choosing to opt out of the GMO experiment.

Are GMOs labeled?
Unfortunately, even though polls consistently show that a significant majority of Americans want to know if the food they’re purchasing contains GMOs, the powerful biotech lobby has succeeded in keeping this information from the public. In the absence of mandatory labeling, the Non-GMO Project was created to give consumers the informed choice they deserve.

Where does the Non-GMO Project come in?
The Non-GMO Project is a non-profit organization with a mission of protecting the non-GMO food supply and giving consumers an informed choice. We offer North America’s ONLY third party verification for products produced according to rigorous best practices for GMO avoidance (for more info, click here). Our strategy is to empower consumers to make change through the marketplace. If people stop buying GMOs, companies will stop using them and farmers will stop growing them.

Do Americans want non-GMO foods and supplements?
Polls consistently show that a significant majority of North Americans would like to be able to tell if the food they’re purchasing contains GMOs (a 2008 CBS News Poll found that 87% of consumers wanted GMOs labeled). And, according to a recent CBS/New York Times poll, 53% of consumers said they would not buy food that has been genetically modified. The Non-GMO Project’s seal for verified products will, for the first time, give the public an opportunity to make an informed choice when it comes to GMOs.

How common are GMOs?
In the U.S., GMOs are in as much as 80% of conventional processed food. Click here for a current list of GMO risk crops.

What are the impacts of GMOs on the environment?
Over 80% of all GMOs grown worldwide are engineered for herbicide tolerance. As a result, use of toxic herbicides like Roundup has increased 1S times since GMOs were introduced. GMO crops are also responsible for the emergence of “super weeds” and “super bugs:’ which can only be killed with ever more toxic poisons like 2,4-D (a major ingredient in Agent Orange). GMOs are a direct extension of chemical agriculture, and are developed and sold by the world’s biggest chemical companies. The long-term impacts of GMOs are unknown, and once released into the environment these novel organisms cannot be recalled.

How do GMOs affect farmers?
Because GMOs are novel life forms, biotechnology companies have been able to obtain patents with which to restrict their use. As a result, the companies that make GMOs now have the power to sue farmers whose fields are contaminated with GMOs, even when it is the result of inevitable drift from neighboring fields. GMOs therefore pose a serious threat to farmer sovereignty and to the national food security of any country where they are grown, including the United States.

How can I avoid GMOs?
Choose food and products that are Non-GMO Project Verified!

Click here to see a complete list.

GMO

What You Should Know About GMO’s
February 3, 2012
Hosted by Jill Buck

 Are genetically modified seeds and crops safe for human consumption? Are they already in our food supply? Should genetically modified food be labeled as such, so consumers can decide for themselves if they wish to purchase it? 

Go Green Radio interviewed Megan Westgate, Executive Director of the Non GMO Project (www.nongmoproject.org). Megan discussed GMO’s from the perspective of consumers, farmers, and the future of our global food supply.  It's a great interview to listen to. Click Here to visit the site and listen to the Interview

I'm very passionate about safe foods, and knowing what I'm eating.  We all need to make the personal choice about what we eat and don't eat...but key in knowledge!  Too many people have a mind frame of ignorance is bliss...but I find this a very dangerous state of mind.  Make educated decisions, especially when it comes to your health and the health of your loved ones.

Dark Chocolate

Cocoa from dark chocolate lowers risk from colon cancer

 Colon cancer is the third leading cause of cancer deaths annually, a statistic that remains constant despite increased awareness of the deadly disease. Researchers from the Science and Technology Institute of Food and Nutrition in Spain have published the result of a study in the journal Molecular Nutrition & Food Research detailing the potent anti-carcinogenic effect of the natural chocolate compound, cocoa. Scientists determined for the first time that regular consumption of cocoa negates the inflammatory effect of digestive oxidative stress that results in intestinal complaints and is a precursor to the genesis of colon cancer. Cocoa is now considered a superfood as it has been shown to improve blood lipids and help prevent cardiovascular disease in past research. The result of this current study demonstrates that a daily dose of the compound can help prevent colon cancer progression.

Researchers studied rats that had been fed a cocoa-rich diet consisting of twelve percent cocoa, as compared to a control group that received the same diet with the chocolate compound enrichment. Both groups were exposed to a chemical known to induce colon cancer. Animals such as mice and rats have been used for decades to conduct this type of research because they exhibit a similar line of carcinogenesis that is comparable to humans.

Cocoa polyphenols from dark chocolate significantly lower colon cancer risk

The study leader, Dr. Maria Angeles Martin Arribas noted "Being exposed to different poisons in the diet like toxins, mutagens and pro-carcinogens, the intestinal mucus is very susceptible to pathologies...foods like cocoa, which is rich in polyphenols, seems to play an important role in protecting against disease." After a period of eight weeks, the scientists were able to confirm the protective effect of cocoa polyphenols in protecting against this insidious form of digestive cancer.

The study results showed a marked decrease in the number of pre-malignant neoplastic crypts in the lining of the colon in the cocoa-treated group as compared to the control animals. Further, the researchers found a rise in antioxidant defenses in the supplemented rats and a decrease in oxidative stress biomarkers that are known to be protective against chemical exposure and the prevention of colorectal cancer.

The team concluded that the protective effect of the bioactive compounds in cocoa stopped cell-signaling pathways that typically promote cell proliferation and lead to tumor development. The treated animals also exhibited a much higher degree of apoptosis, or normal programmed cell death of potentially cancerous tissues. It is important to note that milk chocolate is not a good source of cocoa due to its low concentration of the polyphenol and high sugar content, known to promote cancer. Choose a dark chocolate with a minimum 70 percent cocoa content to significantly lower the risk associated with colorectal cancer.

Some wonderful ways to incorporate the health benefits of cocoa into your every day life include making your own hot cocoa (for a cold weather treat), using healthy sweetener substitutes, such as palm sugar instead of refined sugar, or making your own raw chocolate, using dates to sweeten it.  Those 2 are my favorite ways to get my chocolate in!  If I'm craving a melt-in-your-mouth chocolate bar I look to get 80% cacao or higher chocolate bars, usually organic too, because I'm now used to the high cocoa content and those usually don't contain soy lecithin, but anything over 70% cocoa is a great choice over milk chocolate for health benefits.

Corn and Soy products

Did you know? Nearly all corn and soy products purchased at grocery stores are genetically modified and may place your health at risk

More than 90 percent of all soybeans grown in the United States are genetically modified (GM) for herbicide resistance and are consequently sprayed with massive quantities of those toxic chemicals. Fully 85 percent of all corn grown in the country is also genetically engineered, either for herbicide resistance or to produce pesticides within its tissues. Since farmers sell their corn and soy to large distributors who mix the product together for processing, this essentially means that 100 percent of non-organic corn and soy products on the US market are GM.

And since soy and corn derivatives are so ubiquitous in packaged food, the Grocery Manufacturers of America has estimated that as much as 80 percent of processed food on US shelves contains GM ingredients. This includes breakfast cereals and other products labeled "natural" or "all natural." (http://www.naturalnews.com/033838_breakfast_cereals_GMOs.html)

GM crops are simply unsafe. They expose people to novel and potentially dangerous allergens and to higher levels of pesticides. Animals grazing on GM crops have died from ruptured internal organs. Yet this is the type of food making up 80 percent of packaged food today, and the only way to avoid it is to buy organic food or grow your own.

Tip: Foods labeled USDA Organic do not contain any substantial level of genetically engineered ingredients, but due to cross-contamination of crops, even organic products almost always contain trace levels of GMOs.

Source: 25 Amazing Facts About Food, authored by Mike Adams and David Guiterrez. This report reveals surprising things about where your food comes from and what's really in it! Download the full report (FREE) by clicking here. Inside, you'll learn 24 more amazing but true facts about foods, beverages and food ingredients. Instant download of the complete PDF. All 25 facts are documented and true.