Mushrooms For Breast Cancer Prevention
by Michael Greger M.D.
Breast cancer can take decades to develop, so “early” detection via
mammogram may be too late. The breast cancer you may feel one day as a
lump in the shower, may have started 20 years ago. We now suspect that
all the epithelial cancers: breast, colon, lung, pancreas, prostate,
ovarian—the ones that cause the vast majority of cancer deaths—take up
to 20 years or more to manifest. By the time it’s picked up it may have
already been growing, maturing, scheming for years, acquiring hundreds
of new survival-of-the-fittest mutations to grow even quicker and better
undermine our immune system. Early detection may in effect be really,
really late detection.
People are considered “healthy” until they show symptoms, so if we’ve
been harboring a malignancy for 20 years we may feel all right, but we
haven’t been. Thus, many people who do the right thing and improve their
diet in hopes of preventing cancer may, at that very moment, be
treating it as well. In this way,
cancer prevention and treatment may sometimes be the same thing.
What new developments are there are in the battle against breast
cancer? Well, most breast tumors are estrogen receptor positive, meaning
they respond to estrogen; estrogen makes them grow. The problem for
tumors in postmenopausal women is that there isn’t much estrogen
around—unless of course you take it in a drug like Premarin (so-named
because it’s made from pregnant mare urine). Premarin appears to
increase the risk of breast cancer (as well as strokes, heart attacks,
and blood clots). Unfortunately, the plant-based bioidentical hormone
replacement therapies don’t appear any safer (see my 4-min. video
Plant-Based Bioidentical Hormones).
Thankfully millions of women stopped taking Premarin in 2002, and we
saw a nice dip in breast cancer rates. Unfortunately, those rates have
since stagnated. Hundreds of thousands of American women continue to get
the dreaded diagnosis every year. So what next?
Well, with no estrogen around, many breast tumors devise a nefarious
plan—they’ll just make their own! Seventy percent of breast cancer cells
synthesize estrogen themselves using an enzyme called aromatase. In
response, drug companies have produced a number of aromatase inhibitor
drugs that are used as chemotherapy agents. Of course by the time you’re
on chemo it can be too late, so researchers started screening hundreds
of natural dietary components in hopes of finding something that targets
this enzyme.
To do this you need a lot of human tissue. Where are you going to get
it from? To study skin, for example, researchers use discarded human
foreskins from circumcision. They’re just being thrown away–might as
well use them! Where are you going to get discarded female tissue?
Placentas. They got a bunch of women to donate their placentas after
giving birth to further this critical line of research.
After years of searching, they found seven
vegetables with significant anti-aromatase activity. You can see the graph in my video
Vegetables Versus Breast Cancer.
Bell peppers, broccoli, carrots, celery, green onions, and spinach
dropped aromatase activity by about 20%, but mushrooms forced down the
estrogen-producing enzyme more than 60%.
Which mushroom worked best? Woodear, crimini, oyster, Italian brown,
enoki, button, stuffing, shiitake, chanterelle, or Portobello mushrooms?
Don’t even try to guess—you won’t get it! Check out my 2-min video
Breast Cancer Prevention: Which Mushroom Is Best? for the answer.
More on the magic of mushrooms in
Making Our Arteries Less Sticky and
Constructing a Cognitive Portfolio. Probably a good idea to cook them, though:
Toxins in Raw Mushrooms.
I also have videos on breast cancer risk in relation to
apples,
broccoli,
exercise,
flax seeds,
green tea,
greens,
meat,
melatonin,
saturated fat,
soy, and
trans fat.